This research study is testing Amphora, an investigational non-hormonal contraceptive product applied to the vagina. We are studying Amphora to see how well it prevents pregnancy. Amphora works by maintaining the vagina’s natural pH balance and forming a protective layer which prevents sperm from reaching the egg. There will be approximately 1300 women enrolled in the study at different research centers across the US. If you join the study, you and your partner will use Amphora as your primary method of birth control for seven menstrual cycles or approximately 7 months.
This study will enroll 1000 women at 16 different sites across the United States to test an investigational copper IUD that is available in Europe but not in the United States. The purpose of this study is to find out how well this investigational IUD prevents pregnancy and whether it causes less vaginal bleeding and cramping than a larger copper IUD currently on the market.